Abstract：Objective To explore the clinical efficacy and prognosis of rabeprazole and omeprazole in the treatment of chronic gastritis.Methods Eighty patients with chronic gastritis admitted to our hospital from January 2023 to January 2025 were selected and randomly divided into a control group (treated with omeprazole) and a study group (treated with rabeprazole), with 40 cases in each group. The inflammatory factors, gastric function indicators, duration of symptom relief, therapeutic effects and incidence of adverse reactions were compared between the two groups. Results After treatment, the levels of inflammatory factors in the study group were lower than those in the control group, the gastric function indicators were better than those in the control group, and the symptom relief time was shorter than that in the control group (P<0.05).There was no statistically significant difference in the therapeutic effect and the incidence of adverse reactions between the two groups(P>0.05).Conclusion Compared with omeprazole, rabeprazole has comparable clinical efficacy in the treatment of chronic gastritis, but it has more advantages in reducing inflammation levels, regulating the gastrointestinal tract and shortening the time for symptom relief.
Keywords : Rabeprazole; Omeprazole; Chronic gastritis; Clinical efficacy
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